ABSTRACT
To determine the frequency of Gestational Diabetes in obese patients. Cross sectional study This study was carried out at Obstetrics and Gynaecology Department, Shahina Jamil Hospital, Abbottabad from April 2013 to September 2013. Total 111 patients were included in this study. After an overnight fast [8 hrs] fasting plasma glucose was taken. 75 gm glucose in one glass of water was given to patient. After 2 hours, another plasma glucose test was taken. Gestational Diabetes was diagnosed on basis of fasting plasma glucose level of > 126 mg / dl, 2 hours post-prandial plasma glucose level of more than 199.8 mg / dl. Mean age of patients was 27.7 + 3.3. Gestational Diabetes was found in 21 patients [19.0%]. Mean Body Mass Index [BMI] of patients was 30.80 + 0.44. 24 patients [21.6%] were primigravida and 87 patients [78.4%] were multigravida. The results of present study indicate that obesity is an independent risk factor for adverse obstetric outcome and is significantly associated with an increased gestational diabetes rate
ABSTRACT
To determine fetomaternal outcome of trial of labour in patients with Previous One Ceasarean Section. Descriptive Case Series based on hospital data. This study was conducted at the Obstetrics and Gynaecology Department, Shahina Jamil Teaching Hospital Abbottabad, from February 2013 to August 2013. Total 100 cases were selected. During trial of labour, patients were closely monitored by vital signs, fetal cardiac activity, lower abdominal pain and tenderness, fetal distress. Data was collected on proforma and written informed consent was taken on consent form. The permission was taken for hospital committee and the data was analyzed for results. 61 cases [61 %] had successful vaginal delivery while 39 [39 %] patients ended up with repeat emergency caesarean section after failed trial of labour. Out of 61 vaginal deliveries, 53 cases [86.88%] belong to age group 20-30 yrs, while 8 cases [13.12%] were between 31-40 years. Out of 39 cases, 36 cases [92.30 %] belonged to age group of 20-30 years while 3 cases [7.7 %] had age between 31 to 40 years. Distribution of cases, according to fetal distress in patients with emergency caesarean section shows that out of 39 cases, 12 cases [30.70 %] developed fetal distress and 27 cases [69.23 %] were without fetal distress. This study shows that patients with Previous one caesarean section for non-recurrent indication can be successfully delivered vaginally
ABSTRACT
The optimum pH of fructose-1, 6-diphosphate aldolase from thigh muscles was found to be 9. The pK values of amino acids present at the active centre were found to be 7 and 9.7 corresponding to Imidazolium group of histidine and E1-ammonium group of lysine, respectively. The Km value and Vmax were found to be 63.49 mM and 10 S-L units, respectively